Peak nasal inspiratory flow in children with allergic rhinitis. Is it related to the quality of life?
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Keywords
Allergic rhinitis, Peak nasal inspiratory flow, Quality of life, Children, KINDL-R questionnaire
Abstract
Introduction and Objectives: Allergic rhinitis (AR) is the most common allergic disease in childhood. Nasal obstruction is a typical symptom of AR, however, its quantification by clinical examination is difficult. To provide an objective assessment of nasal patency, the peak nasal inspiratory flow (PNIF) is used. Symptoms of AR have a noticeable impact on the quality of life. The aim of this study was to assess which factors may have an impact on PNIF values and to evaluate the possible relationships between PNIF and QoL in children with AR.
Patients and Methods: We recruited patients aged 6-17 years (n = 208, 89 girls and 119 boys) with AR. All children underwent PNIF measurements. Parents and children completed KINDL-R generic questionnaires, to assess the quality of life of the children.
Results: The average PNIF value was 98.9 ± 37.4 L/min. A very strong (p < 0.001) relationship between the PNIF value and height, age and weight of the child was observed. The sex of the patient has no influence on the PNIF value. We showed that PNIF values significantly increased with each attempt. The children assessed their QoL at 45.6 ± 8.5 points in the KINDL-R questionnaire and the parents rated their children’s QoL at 73.7 ± 10.7 points. We observed a weak negative correlation between PNIF and the QoL based on the parents’ assessment and the child’s self-assessment.
Conclusions: PNIF values depend mostly on height, but also on the child’s age and weight. A learning effect (significant increase in PNIF upon each attempt) was shown. Higher PNIF does not improve the QoL.
References
2. Meltzer EO, Nathan R, Derebery J, et al. Sleep, quality of life, and productivity impact of nasal symptoms in the United States: Findings from the Burden of Rhinitis in America survey. Allergy Asthma Proc. 2009;30:244-54.
3. Everhart RS, Kopel SJ, Esteban CA, et al. Allergic rhinitis quality of life in urban children with asthma. Ann Allergy Asthma
Immunol. 2014;112:365-70.
4. Greiner AN, Hellings PW, Rotiroti G, et al. Allergic rhinitis. Lancet. 2011;378:2112-22.
5. Ravens-Sieberer U, Gosch A, Abel T, et al. Quality of life in children and adolescents: a European public health perspective. Soz Praventivmed. 2001;46:297-302.
6. Krzych-Fałta E, Furmanczyk ´ K, Samolinski ´ B, et al. Nasal patency in Poles in the light of research as part of the project on Epidemiology of Allergic Diseases in Poland. Ann Agric Environ Med. 2016;3:487-90.
7. Modzelewska D, Krzych-Fałta E, Lusawa A, et al. Analiza wyników badania PNIF (Peak Nasal Inspiratory Flow) w ´swietle badan´ ECAP (Epidemiologia Chorób Alergicznych w Polsce). Przeglad˛ Lekarski. 2012;69:10.
8. Dor-Wojnarowska A, Rabski M, Fal A, et al. An attempt to estimate parameters useful for establishing a normal range for peak nasal inspiratory flow. Pneumonol Alergol Pol. 2011;79:320-5.
9. Can D, Gulen F, Tanac R, et al. Value of peak nasal inspiratory flow in Aegean school children. Asthma Allergy Immunol. 2011;9:138-43.
10. Papachristou A, Bourli E, Aivazi D, et al. Normal peak nasal inspiratory flow rate values in Greek children and adolescents. Hippokratia. 2008;12:94-7.
11. van Spronsen E, Ebbens FA, Fokkens WJ. Normal peak nasal inspiratory flow rate values in healthy children aged 6 to 11 years in the Netherlands. Rhinology. 2012;50:21-5.
12. Starling-Schwanz R, Peake HL, Salome CM, et al. Repeatability of peak nasal inspiratory flow measurements and utility for assessing the severity of rhinitis. Allergy. 2005;60:795-800.
13. Jozefiak T, Larsson B, Wichstrøm L, et al. Quality of Life as reported by school children and their parents: a cross-sectional survey. Health Qual Life Outcomes. 2008;6:34.
14. Meyer M, Oberhoffer R, Hock J, et al. Health-related quality of life in children and adolescents: Current normative data, determinants and reliability on proxy-report. J Paediatr Child Health. 2016;6:628-31.
15. Valero A, Navarro AM, del Cuvillo A, et al. Position Paper on Nasal Obstruction: Evaluation and Treatment. J Investig Allergol Clin Immunol. 2018;28:67-90.
16. Mozzanica F, Gera R, Bulgheroni C, et al. Correlation between Objective and Subjective Assessment of Nasal Patency. Iran J Otorhinolaryngol. 2016;28:313-9.
17. Lara-Sánchez H, Álvarez Nuno˜ C, et al. Assessment of nasal obstruction with rhinomanometry and subjective scales and outcomes of surgical and medical treatment. Acta Otorrinolaringol Esp. 2017;3:145-50.
18. Giotakis AI, Tomazic PV, Riechelmann H, et al. Objective Assessment of Nasal Patency. Facial Plast Surg. 2017;4: 378-87.
19. Nagaraju MK. Peak Nasal Inspiratory Flow Levels in Children With Allergic Rhinitis and Their Health Related Quality of Life (HRQL). World Allergy Organ J. 2012;5:28.
20. Stöcklin L, Loss G, von Mutius E, Weber J, et al. Health-related quality of life in rural children living in four European countries: the GABRIEL study. Int J Public Health. 2013;3:355-566.
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